Some scientific breakthroughs are so transformative that there’s no containing their spread once they’ve seeded. By engineering cellular nuclear reactions with a biochemical twist, the most powerful deactivated Cas9 (dCas9) methyltransferase explodes from the lab of Tomasz Jurkowski at the University of Stuttgart. The free energy of this reaction forges not only a new tool […]
Epigenetics and ncRNA Headlines
Get all the latest highlights from the literature and special features covering trending epigenetics, ncRNA, and gene regulation research.
Once thought to be monogamous molecules characterized by devote linear relationships, chromosomes turn out to be philandering conformation-changers with burning loins of desire concealed between their genes. Coming from the lab of Bing Ren at the University of California, San Diego, a massive analysis of genome-wide chromosome interactions captured by Hi-C uncovers a distinct piece […]
The old adage reads “you are what you eat”, but a tasty new study turned that bland old phrase into “your histones are what you eat!”, and what’s more, those behind the study have worked the mechanistic link. Some of our daily diet (i.e. coffee and candy) acts as an energy and carbon source for […]
After playing hide-and-seq with chromatin for a while, we’re sure you’ve been begging for a new plan of attack to help you see what’s going on. Thankfully, a Northern California collaboration led by the lab of Howard Chang alongside the labs of William Greenleaf, Jan Liphardt, and Jennifer Doudna has brought forth a tactic to […]
A dog walk in the countryside led to Velcro, the search for chest pain therapies gave us (who me?) Viagra, and a messy microbiology lab bench provided penicillin. Some big research discoveries appear to have arrived in an “accidental” form and maybe, just maybe, new research from the laboratory of Déborah Bourc’his can be spoken […]