Turning a cell into an induced pluripotent stem cell (iPSC) is tricky. It turns out that blood cells have an edge—they already epigenetically resemble iPSCs. When U.S. and Chinese researchers poked around the DNA of human CD34+ cells from umbilical cord blood and adult blood, they found that the promoters’ methylation patterns looked a heck […]
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Stem Cell Research Headlines
Get all the latest highlights from the literature and special features covering trending stem cell research and applications.
Growing up, you always hear that drinking alcohol kills brain cells. According to a new report (not to mention a slow recovery from the EpiGenie New Year’s Eve Bash) there’s definitely some truth to that old adage. Researchers at Indiana University looked at alcohol’s effect on neural stem cells (NSCs) during development by running NSC […]
2010 is over, so we’ve decided to take a look back at some of the exciting non-coding RNA work that came out over the last half of the year on topics like iPS cells, miRNA sponges, cancer and biomarkers. Enjoy! miRNAs in iPS cells An important tool for stem cell research, induced pluripotent stem cells […]
DNA methylation was heating up in the second half of 2010 in hot pursuit of determining roles for 5-hydroxymethylcytosine, creating bisufite alternatives and uncovering DNAm’s role in disease. Have a look at some of our favorite articles from the last six months: 5-hmC and Stem Cells Anytime you put together a new biological role for […]
There’s been a deafening buzz lately surrounding a new focus of epigeneticists known as the epithelial-mesenchymal transition (EMT). EMT, the gateway between normal epithelial cells and those that gain mesenchymal properties, is thought to be the point where cancer metastasis kicks off. And now a University of Hong Kong team, led by Hongping Xia reports […]