2010 is over, so we’ve decided to take a look back at some of the exciting non-coding RNA work that came out over the last half of the year on topics like iPS cells, miRNA sponges, cancer and biomarkers. Enjoy! miRNAs in iPS cells An important tool for stem cell research, induced pluripotent stem cells […]
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DNA methylation was heating up in the second half of 2010 in hot pursuit of determining roles for 5-hydroxymethylcytosine, creating bisufite alternatives and uncovering DNAm’s role in disease. Have a look at some of our favorite articles from the last six months: 5-hmC and Stem Cells Anytime you put together a new biological role for […]
There’s been a deafening buzz lately surrounding a new focus of epigeneticists known as the epithelial-mesenchymal transition (EMT). EMT, the gateway between normal epithelial cells and those that gain mesenchymal properties, is thought to be the point where cancer metastasis kicks off. And now a University of Hong Kong team, led by Hongping Xia reports […]
We’re not calling the miRNA 23a,27a,24-2 cluster a bunch of biological bad-guys, but if you’re a progenitor cell hoping to one day become an osteoblast, then they aren’t exactly your best friends. A new study reveals that the miRNA 23a,27a,24-2 cluster is at the center of a regulatory network that controls osteoblast differentiation. The new […]
How can you mend a broken heart? Well if researchers at Stanford University are right, then one day all you’ll need are some stem cells and miR-499 to cure a bad case of heartache (well, at least the kind that follows a heart attack. The bad breakup kind will still be up to relationship experts […]