Gene editing with CRISPR/Cas9 is here, there, and everywhere. We have seen gene editing in human somatic cells, pluripotent stem cells, and even embryos. However, we should also be looking at CRISPR-based gene editing somewhere else: in a living, breathing human. The question is – where does the current technology stand on the in vivo […]
Keeping up with the rapidly evolving technology landscape for epigenetics and non-coding RNA research can be daunting. Learn more about the available methods out there and stay on top of the latest developments in our Technology section.
They help cook dinner, clean the dishes, and sweep up afterward. They also build our cars, help us explore space, and now they may be on the verge of aiding in highly complex tasks in the laboratory. In particular, robot-based automation is being explored as a means to enhance efficiency in laboratories studying pluripotent stem […]
If a picture is worth a thousand words then surely a video must be worth more? So far, our knowledge about DNA methylation has been limited to a comic strip of static images at different stages. That may all be about to change with a new tool reported by the lab of Rudolf Jaenisch, which […]
Chromatin immunoprecipitation (or ChIP) is a handy technique to study epigenetic profiles, but only if you have enough cells. The main problem with ChIP is that it can be a “greedy” technique that uses large numbers of cells while giving back the bare minimum of DNA as a result. This is problematic for the study of genome-wide […]
Recent work by Seok Hyun Yun and Matjaž Humar has shown us that laser shows aren’t just for Pink Floyd fans. These crafty researchers incorporated specific structures into individual cells, turning them into self-contained “microlasers”. In its simplest form, laser (or light amplification by stimulated emission of radiation) technology uses an energy source to amplify photons bouncing between reflective […]