EPI Genie
CHROMATIN
HATs OFF TO HISTONES

Travel can be one of the most rewarding pastimes. Immersing one’s self in other cultures, or maybe just a nice relaxing holiday at the beach is the perfect cure for work malaise. The only downside is packing.

There’s nothing redeeming about packing; and unpacking is even worse, but it is necessary unless of course you’re living in an American Express commercial where the couple loses their luggage and say shucks and go on a shopping spree in St. Barts.

That’s why we at EpiGenie tip our HATs to histones. These little cellular sherpas pack, unpack, and pack again all day every day, never questioning what other cellular functions may be more rewarding, just packing…..and unpacking, guiding some 3+ meters of DNA into the overhead bin of the nucleus.

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METHOD SPOTLIGHT
CHROMATIN DATABASES AND BIOINFORMATICS TOOLS
  • ChIPOTle:  A Microsoft Excel Macro that facilitates ChIP Tiling array data in yeast.
     
  • Mpeak:  A model-based method for identifying peaks in ChIP array data.
     
  • MPromDb:  An mammalian promoter database integrated with experimental data of transcriptional start site, cis-regulatory elements, CpG island, and ChIP-chip data, featuring useful visualization tools.
EPI Genie