With recent exciting reports demonstrating that adenine can be methylated and exist as N6-methadenine (6mdA) in animal DNA, this presents a timely opportunity for this one day workshop to discuss the many questions this raises.
A lot of research focuses on cytosine methylation (5mdC) in CpG dinucleotides of DNA. However with the expansion of known epigenetic modifications in animal DNA, including methydation of non-CpG cytosines, as well as three 5mC-derivitatives: 5hmdC, 5fdC and 5cadC, this meeting will offer delegates in the field the opportunity to discuss the current state and identify the challenges and future directions related to studying the biological importance of these enigmatic DNA modifications