Despite an investment of tens of billions of dollars each year, heart failure (HF) therapies have limited efficacy in reducing disease progression. Recent insights in fundamental myocyte biology, HF etiologies and pathogenic mechanisms are propelling new strategies to treat and prevent HF. This meeting will explore biologic and technical advances that inform the genetic architecture, molecular pathogenesis and innovative approaches to treat HF. This comes at a time when very large human HF datasets are available and can be interrogated using advanced computational and bioinformatic approaches. Specific aims are to: 1) Consider genes, molecules, signaling pathways and biomarkers involved in systolic and diastolic HF in humans; 2) Explore disease mechanisms underlying HF in model systems; 3) Understand the role of epigenetics, miRNAs and lncRNAs in HF pathogenesis; and 4) Review translational programs in genomic, pharmacologic and cell-based therapeutics to treat HF. The outcomes of this meeting should be far-reaching for basic, translational and clinical communities.
- Conferences
- Heart Failure: Genetics, Genomics and Epigenetics
Heart Failure: Genetics, Genomics and Epigenetics
Keystone Symposia - 03 Apr 2016
Summary
Topics
Details
Meeting Summary
Topics Include
- Heart Failure 2016: Syndromes, Mechanisms and Treatments
- Cardiovascular Tissue Engineering and Organs on Chips (Joint)
- Molecular Aspects of Muscle Cell Contractility and Relaxation
- Novel Therapeutic Approaches to Fix Broken Hearts (Joint)
- Single Cell and Liquid Biopsy Genomics of Cancer • Sarcomere Genetics: So What’s New?
- Systems Dissection of Cardiac Failure
- Aging Hearts
- Workshop and Panel 1: Genetics of Heart Failure
- Workshop and Panel 2: Epigenetics and Genomics of Heart Failure
joint with Cardiac Development, Regeneration and Repair
Meeting Details
Date | 03 Apr 2016 |
Location | Snowbird Resort Snowbird, Utah, USA Get Directions |
Organizers | Stuart A. Cook, Christine E. Seidman and Yigal M. Pinto |