This course brings together biochemists and bioinformaticians to integrate the information encoded in the nuclear proteome and its interaction with DNA to better understand the processes that govern epigenetic inheritance.
The goal of this Lecture Course is to foster scientific exchange between scientists working on the nuclear proteome, the dynamic behavior of proteins in the nucleus and the integration and visualization of protein and DNA networks. This Course is unique in that it focuses on nuclear proteomics and data integration in order to enhance our understanding of the molecular mechanisms that mediate epigenetic processes.
There will be dedicated sessions on the proteomic analysis of histone modifications, defined chromosomal domains, functional proteomics together with sessions on quantitative proteomics, emerging technologies and bioinformatic analysis of large proteomic datasets and their visualization. The Course includes lectures by leading researchers in the field, two poster sessions, oral presentations by junior researchers selected from the abstracts, meet-the-experts sessions and a round table discussion on emerging concepts and future developments in the field. A major feature of the Course is the problem solving sessions, whereby participants can discuss specific issues or problems of their projects in a one-to-one private session with one of the expert speakers of the Course.