Genome-wide association studies and the emergence of new sequencing technologies has helped refine our understanding of the genetic architecture of disease. This past year has seen a continuing increase in the scale of genomic data sets and important strides in identifying functionally and clinically relevant genetic variation.
This year’s conference will feature leading examples of genetic discovery efforts for common diseases using a range of technologies, including genotyping arrays, as well as targeted-, exome- and whole-genome sequencing. We will also focus on approaches to characterize regulatory variation, how to use model organisms as a way to move from association to function and increase the mechanistic understanding of disease. The meeting will highlight important recent efforts in clinical translation and survey a range of global genomic medicine programmes.