While solos are the key to some of your favorite tunes, a masterpiece as magnificent as chromatin conformation is hardly the work of a one-man band; instead, it takes an orchestra of histone modifications to complement and counterpoint cohesin´s sonorific solos. Now, a duet from the labs of Francois Spitz (Pasteur Institute, France) and Leonid […]
Epigenetics and ncRNA Headlines
Get all the latest highlights from the literature and special features covering trending epigenetics, ncRNA, and gene regulation research.
While it’s never a great idea to stare directly into the sun, a DNA methyltransferase (DNMT) eclipse brought to you by the SunTag system may just steal your eyes during its totality. This designer epigenome editing system comes to you from the labs of Margaret A. Goodell and Wei Li at Baylor College of Medicine […]
On any good pirate map, ‘X’ marks the spot for buried treasure. It turns out the same is true in epigenetics: xQTL analysis marks the spot for buried GWAS associations. Genome-wide association studies (GWAS) have been instrumental in identifying single nucleotide polymorphisms (SNPs) associated with human disease. However, finding the biological relevance of such SNPs […]
With age comes wisdom, and also a changing methylation landscape. These changes in methylation can predict life expectancy, with a subset referred to as the ‘epigenetic clock’. For those of us looking to add more time, caloric restriction has been shown to increase life expectancy and reduce the incidence of age-related diseases. Despite three decades […]
While plastic is fantastic, the luxury of our synthetic world comes at a price: plasticizing agents can affect our chances of bringing new life into that world thanks to our environmentally-responsive sperm. Phthalates, which are common plasticizing agents, disrupt the endocrine system and are present in food packaging, personal care products such as shaving cream, […]