While we’ve been captivated by the powerful applications of precision epigenetic editing via deactivated Cas9 (dCas9), we’ve also been mesmerized by the fact that epigenetic editing doesn’t always work as expected. Building on our need to take a step back and look at the bigger picture, new findings from the lab of Alexander Meissner at […]
Epigenetics and ncRNA Headlines
Get all the latest highlights from the literature and special features covering trending epigenetics, ncRNA, and gene regulation research.
While the DNA editing function of CRISPR/Cas9 systems may appear to hog the limelight, we believe that a new SunTag approach for CRISPR/Cas9-mediated induced pluripotent stem cell (iPSC) reprogramming via epigenome editing deserves its day in the sun! The exciting reprogramming strategy utilizes an endonuclease dead Cas9 (dCas9) fused to a repetitive protein scaffold known […]
While aging works wonders for the taste of our ever-accumulating wine collection, the passage of the years is not as kind to our memories! To fully decipher the processes underlying learning and memory differences in the aging brain, the lab of Iva Zovkic at the University of Toronto Mississauga (Canada) recently expanded on past work […]
A wise man once said that time is relative, and while physics was on his mind, it seems that biology should have been as well. For instance, patients with bipolar disorder suffer from accelerated aging. However, examinations of telomere length have given mixed results, and this inspired the lab of Joao Quevedo in the University […]
People can have some pretty strange tastes. From mayonnaise on fries to syrup on spaghetti, there’s no accounting for personal preference. Proteins can have some interesting preferences too, where some regions of the genome look better than others. To get at these preferences, a recent publication from the Laboratory of Bing Ren at UC San […]