So you’ve been performing global methylation analyses for months and want to start validating your jaw dropping findings in a broader sample set?  We don’t blame you.

A few years ago obtaining quantitative DNA methylation information at CpG sites of interest in a larger number of samples meant a whole lot of primer design, assay optimization, and brute force.

Today using tools like EpiTYPER®, navigating through CpG islands and other areas of interest is a walk in the park with:
 

EpiDesigner (www.epidesigner.com) is a free program that cranks out optimized sets of primers for bisulfite converted DNA. All you need to do is:

1. Enter the sequence of your region of interest (manually, or in a batch file upload)
2. Run Program
3. Choose from the recommended primer sets that best suit your experimental goals

If the idea of incorporating another primer design program into your life isn’t that enticing, you can choose from hundreds of pre-validated primer sets with the Human and Mouse EpiPanels.

The Validated EpiPanels target many of the key regions that exhibit aberrant DNA methylation patterns in disease and development.

Sequenom’s current EpiPanels include the:

• Human Standard EpiPanel
• Cancer EpiPanel
• Imprinting EpiPanel
• Mouse Standard EpiPanel

 Download the EpiPanel content lists and check them out for yourself.

Visualizing your experimental results is straightforward with EpiTYPER Analysis Software. Intuitive buttons guide you to select your data set, while stacked display panes allow you to visualize mass spectrum, sequence information, CpG methylation status and customize the way you view your results.