SeqWright - Bisulfite Sequencing Service
Methylation of Cytosine-Guanine (CpG) dinucleotides in genomic DNA has been correlated to gene silencing, and is regarded as one of the most significant epigenetic events. In particular, CpG methylation in the promoter region of certain genes has been observed as the earliest and most frequent alteration in some cancers by causing inactivation of tumor suppressors. [...]
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