Global DNA Methylation Detection

Global DNA Methylation Detection provides a method to measure global DNA methylation shifts.

- EpiSeeker methylated DNA Quantification Kit (Colorimetric)

Product Overview: DNA methylation is a covalent modification of the cytosine ring at the 5′ position, resulting in 5-methylcytosine (5-mC). In somatic cells, 5-mC is found almost exclusively in the context of paired symmetrical methylation of the dinucleotide CpG. The biological important of 5-mC as a major epigenetic modification in phenotype and gene expression has [...]

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- EpiSeeker methylated DNA Quantification Kit (Fluorometric)

Product Overview: DNA methylation is a covalent modification of the cytosine ring at the 5′ position, resulting in 5-methylcytosine (5-mC). In somatic cells, 5-mC is found almost exclusively in the context of paired symmetrical methylation of the dinucleotide CpG. The biological important of 5-mC as a major epigenetic modification in phenotype and gene expression has [...]

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- Imprint® Methylated DNA Quantification Kit

The Imprint Methylated DNA Quantification technology provides a rapid and reliable method to measure global DNA methylation shifts. Compared to the conventional methods of analyzing hypo- and hyper- global methylation like reverse HPLC, MALDI-TOF-MS, TLC, etc. Sigma’s Imprint Methylated DNA Quantification Kit (MDQ1), allows researchers to spend less time in the lab, with less hazardous components [...]

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