Human recombinant HDAC3/NCOR1 produced in insect cells Background Information: Unlike other class I HDAC enzymes, HDAC3 is found in co-repressor complexes with the SMRT/N-CoR proteins. HDAC3 contains a unique domain structure which includes both nuclear localization and nuclear export sequences. HDAC3 has been implicated in cancer, as HDAC3 inhibitors produce anti-proliferative effects in various cancer […]
- Millipore
HDAC6 (His-tag) human recombinant
Human recombinant HDAC2 (1-488) (His-tag) produced in insect cells Background Information: Histone deacetylase 6 (HDAC6) is member of the class II HDAC family, shich share significant sequence homology to the yeast HDA1 protein. HDAC6 is unique among human HDACs in having two full deacetylase domains. As a tubulin deacetylase, HDAC6 may act to promote autophagic […]
CBP (catalytic domain) human recombinant
CBP (catalytic domain) human recombinant expressed in E. Coli Background Information: Although originally termed histone acetyltransferases (HATs) for their lysine acetylation activity on histone N-terminal tails, p300 and its paralogue, CBP, have been shown to acetylate a variety of non-histone proteins including p53, DNA polymerase ß and nuclear import factors. p300/CBP acetylations play regulatory roles […]
p300 (catalytic domain) human recombinant
Human recombinant p300 (catalytic domain) expressed in E. Coli Background Information: Although originally termed histone acetyltransferases (HATs) for their lysine acetylation activity on histone N-terminal tails, p300 and its paralogue, CBP, have been shown to acetylate a variety of non-histone proteins including p53, DNA polymerase ß and nuclear import factors. p300/CBP acetylations play regulatory roles […]
PCAF human recombinant
Human recombinant PCAF expressed in E. Coli Background Information: PCAF (p300/CBP-associated factor) is involved in acetylation of histones H3 and H4, and a number of transcription factors.