M220™ Focused-Ultrasonicator

Benchtop shearing for NGS and ChIP M220 Focused-ultrasonicator is designed for Next-Gen Sequencing and ChIP applications. The compact size and ease-of-use of the M220 Focused-ultrasonicator make it the ideal Chromatin shearing solution for any lab.  Compatibility with the truChIP™ Low Cell Chromatin Shearing kits provides sensitive ChIP assays with fewer than 1 million cells. Integrated temperature control within the M220 provides real-time temperature control, preserving your sample while eliminating the need for external chillers or the hassle of constantly adding ice and monitoring the system.  Furthermore, the medical-grade ultrasonic frequency allows the use of the M220 directly on any benchtop without special hearing protection or enclosures. Covaris AFA (Adaptive Focused Acoustics™) transmits acoustic energy at ultrasonic frequencies (500kHz) with very short wavelengths (~3mm), focusing the energy into your sample and controlling precisely the shearing forces that fragment nucleic acids to the selected size. The process is isothermal, non-contact, and quiet..  The AFA technology in the M220 eliminates operator induced variations, improves recoveries, and increases efficiency, providing sensitive, standardized, and reproducible results.

  • Designed for bench-top NGS and ChIP applications
  • Compatible with truChIP Low Cell Chromatin Shearing kits
  • Integrated chiller saves space and cost
  • Start up and ready to go in less than 2 minutes
  • No hearing protection required
  • Reproducible results, users to users, year after year