Benchtop shearing for NGS and ChIP
M220 Focused-ultrasonicator is designed for Next-Gen Sequencing and ChIP applications. The compact size and ease-of-use of the M220 Focused-ultrasonicator make it the ideal Chromatin shearing solution for any lab. Compatibility with the truChIP™ Low Cell Chromatin Shearing kits provides sensitive ChIP assays with fewer than 1 million cells.
Integrated temperature control within the M220 provides real-time temperature control, preserving your sample while eliminating the need for external chillers or the hassle of constantly adding ice and monitoring the system. Furthermore, the medical-grade ultrasonic frequency allows the use of the M220 directly on any benchtop without special hearing protection or enclosures.
Covaris AFA (Adaptive Focused Acoustics™) transmits acoustic energy at ultrasonic frequencies (500kHz) with very short wavelengths (~3mm), focusing the energy into your sample and controlling precisely the shearing forces that fragment nucleic acids to the selected size. The process is isothermal, non-contact, and quiet.. The AFA technology in the M220 eliminates operator induced variations, improves recoveries, and increases efficiency, providing sensitive, standardized, and reproducible results.
- Designed for bench-top NGS and ChIP applications
- Compatible with truChIP Low Cell Chromatin Shearing kits
- Integrated chiller saves space and cost
- Start up and ready to go in less than 2 minutes
- No hearing protection required
- Reproducible results, users to users, year after year