Interview with Dr. J Keith Joung, MD, PhD at Keystone Symposia’s Precision Genome Engineering and Synthetic Biology: Designing Genomes and Pathways Moving Genome Editing into the Clinic My laboratory is focused on genome editing technologies and, more recently, on epigenome editing technologies as well. I got into this field first through protein engineering. So I was […]
- thought leaders
Get up close and personal with some of the world's top epigenetics and non-coding RNA thought leaders.
Interview with Dr. Blake Weidenheft at Keystone Symposia’s Precision Genome Engineering and Synthetic Biology: Designing Genomes and Pathways The Early Days of CRISPR I was one of the earlier people involved in the CRISPR– in CRISPR biology. And so we didn’t really come at this with the intent to try to develop some new genome […]
Interview with Dr. Jennifer Phillips-Cremins at Keystone Symposia’s Precision Genome Engineering and Synthetic Biology. My lab is really focused on understanding the epigenetic mechanisms that regulate early brain development. And the, sort of traditional way of studying epigenetic marks, is to zoom in and really focus on a particular modification at a precise location in […]
Interview with Dr. Andrew Ellington at Keystone Symposia’s Precision Genome Engineering and Synthetic Biology: Designing Genomes and Pathways Parts, Circuits, and Systems So in directed evolution, what you’re generally trying to do is to optimize function. And that can mean a lot of different things. But if we keep within the synthetic biology paradigm, we […]
Dr. Andrew Feinberg discusses recent work that has shed new light on the epigenome and it’s role in cancer. Abstract: We and our collaborators have been developing efforts toward whole genome approaches to epigenetic analysis of human disease, including array-based analysis and whole genome bisulfite sequencing. Surprising results have been the discovery of CpG island shores and large hypomethylated […]