Can Disrupting Chromatin Interactions Stop SARS-CoV-2 in its Tracks?February 21, 2022Viral infections can appear like a runaway train, careering through the human body without a brake in sight; however, the meandering journey taken for the development of antivirals has now discovered a new way to stop runaway SARS-CoV-2 infections in their tracks thanks to CRISPR technology and a trip through the chromatin landscape of infected […]
Single-Cell ATAC-seq Shows that Chromatin Remodeling Allows Immune Cells to Remember COVID-19June 24, 2021While few will remember the last eighteen months with any great fondness, the memory of our immune cells represents a critical facet controlling long-lasting responses induced by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and exposure to vaccines. In an unforgettable study, researchers led by Liang Chen, Mark M. Davis, and Pengyuan Yang now demonstrate […]
Storm Chasing: Cell-Free DNA Methylation Tracks the Severity and Location of COVID-19 DamageJanuary 25, 2021As the COVID-19 cytokine storm brews in our bodies, the severity and location of the damage remains uncertain. However, exciting new findings from a storm chasing team led by Iwijn De Vlaminck (Cornell University) show that cell-free DNA (cfDNA) methylation profiles can track the affected organs and severity of COVID-19 damage in patients. Although we’ve seen that DNA […]
DNA Methylation Contributes to the Chaos and Complications of COVID-19December 14, 2020While the cough was the cardinal consideration, COVID-19 has been causing chaos in every organ system, including lungs, heart, brain, blood, liver, and skin. In fact, the involvement of these non-lung systems predicts increased mortality and new research now shows that DNA methylation is a contributor to COVID-19. Researchers from the laboratory of Arjun Deb […]
