Hypermethylated Pockets within Hypomethylated Genomic Regions Defines Cancer CellsDecember 5, 2011What makes a cell become a cancerous? We’d all love to know that, right? Well, new research has gotten a little bit closer to figuring out key epigenetic differences between cancer and normal genomes. It turns out that the DNA methylation patterns of these cells differ drastically, no surprise there, but it’s the genomic context […]
Get Captivating Performance with Zymo’s Genome-wide 5-hmC Analysis ServiceNovember 29, 2011The interest in 5-hydroxymethylcytosine (5-hmC) seems to be increasing faster than the national debt, but there still aren’t many tools available to aid scientists in understanding the 6th base, especially in a genome-wide context. Most current antibody and IP-based approaches are useful but can be a little difficult when applied to NGS. Fortunately, the methylation […]
EpiGenie Review: DNA Methylation in CancerNovember 28, 2011DNA Methylation definitely has a major role in cancer, but with the all of the different tissue types and cancer variations, it’s been nearly impossible to define exactly what that role is. That hasn’t stopped dedicated researchers from chipping away at the task, though…or EpiGenie from covering it. Check out the advances in understanding DNAm […]
Socio-Economic Status Leaves A Methyl Mark on DNANovember 9, 2011Candidates for public office never seem to learn that you can’t escape your past. It’s almost like they’ve never even heard of Google or YouTube or something! Speaking of not letting go of the past, we’ve seen a few papers recently suggesting that some epigenetic changes in early life can stick around for decades. Now, […]
Epigenetic Marker Maternal Blood Prenatal Trisomy 21November 8, 2011Screening for trisomy 21, or Down Syndrome, is a terrifying experience for soon-to-be parents that’s made even worse by the anxiety of the invasive procedures used in today’s testing methods. Soon, though, new diagnostics based on epigenetic markers should be able to indicate prenatal trisomy 21 from just a bit of mom’s blood. A new […]
