Natural Disasters Impact DNA MethylationOctober 16, 2014As Polar Vortex II approaches, you’ll be interested in a recent study highlighting the impact of environment stressors on the epigenome. Prenatal maternal stress exposure is known to adversely affect offspring in a number of ways, depending on the nature of the exposure, but is typically studied in common exposures like diet, alcohol, and lead. But this has left the […]
Epigram: Predicting the Human Epigenome from DNA MotifsOctober 16, 2014There’s no denying the power of technology in our lives, whether it be your latest and greatest iPhone bending in your pocket or it be getting the technology to do something more useful, like predict the entire epigenome and how it functions in the regulation of gene expression. We’ve always loved a good tool and/or […]
Are LncRNAs the Future of Non-Invasive Prostate Cancer Testing?October 9, 2014Prostate cancer is the leading cause of mortality in North-American men and as a result many are forced to the clinic for some rather invasive biopsies, but thanks to some cool epigenetics involving lncRNAs, those once dreaded trips to the doctor’s office may soon be replaced a much less invasive urine test. Ranjan Perera and crew […]
Maternal Care Causes Variation in Behavior and Gene Regulation in FemalesOctober 1, 2014Life experiences shape us in ways that are hard to imagine, whether it’s a catch-phrase from a favorite TV show slipping into our vocabulary ,or how much your mother licked you while you were child (We know that sounds weird for humans, but licking just happens to be a measure of maternal care in rodents). […]
Inheritance of Histone Mod Caught at Cell divisionSeptember 29, 2014Transgenerational Epigenetic Inheritance is one of our favorite topics, it’s done a great job of showing old school Mendelian inheritance who’s boss by creating the molecular complexity of complex traits. With phenotypes and exposures aplenty, the one thing that has been missing is catching the inheritance of an acquired epigenetic mark in the act. And that’s just what a […]
