Histone Serotonylation: From Boosting Moods to Regulating Brain Tumor ProgressionAugust 19, 2024While many know that serotonin impacts mood and emotions, a smattering of studies have found that this neurotransmitter can modify histones and regulate gene expression. Now, fascinating new research reveals that histone serotonylation contributes to the regulation of aggressive brain tumors, playing a role in the complex interactions taking place between neuron–tumor signaling, epigenetics, and […]
Keeping up With Epigenetic Clocks: PRC2-AgeIndex Measures Gains of DNA Methylation Across the GenomeAugust 6, 2024While it may seem like it’s harder to keep up with epigenetic clocks than with the Kardashians, this is one you’re not going to want to miss. Many epigenetic clocks people use to assess aging are built on the DNA methylation status of a few CpGs, and it’s unclear how these sites are related to […]
CoRSIVs in Cows? Targeting a DNA Methylation Bullseye May Improve Livestock Farming!August 5, 2024Finding informative epigenetic targets in the genome is no easy task; however, cleverly composed studies previously reported on the discovery of correlated regions of systemic interindividual variation (or CoRSIVs) in humans – DNA methylation patterns that vary between individuals but remain consistent across tissues. Now, this talented team sets its sights on understanding this level […]
The Epigenetics of Exercise: Acvr1c Improves Learning and MemoryJuly 24, 2024Exercise can boost your mood and improve heart and bone health. Now, a talented team uncovers the epigenetic mechanisms behind another good reason to hit the gym. Working out can help with learning and long-term memory via Acvr1c, a member of the TGF-beta family. Gym rats—er, exercising mice—can learn under “subthreshold training” conditions after a workout, […]
PaleoHi-C Makes a “Mammoth” Genome Architecture DiscoveryJuly 22, 2024Certain scientific findings may be considered colossal or even epic in scale; however, few compare to a “mammoth” new study describing the three-dimensional genome architecture of preserved cells from a 52,000-year-old animal skin sample thanks to a primeval-sounding yet cutting-edge technique known as PaleoHi-C! Epigenetics research goes pre-historic! A veritable “stampede” of researchers led by […]
