SPRITE: A Refreshing New Approach for Identifying Higher-Order Genomic StructureJune 11, 2018Are you looking for a refreshing new nuclear organization assay this summer? Well look no further than SPRITE, it will quench your thirst for a better DNA conformation assay. There are a lot of methods for assessing higher-order DNA structure, but they mostly fall into two categories: proximity ligation and in situ imaging. Proximity ligation […]
Mammalian MicroRNA Travels into the Unknown Territory of the Nucleus to Epigenetically Silence Gene ExpressionJune 9, 2018While we are accustomed to seeing soccer players stroking a ball up and down grassy white-lined pitches and actors waltzing down the red carpet wearing a sharp suit or a stunning dress, we occasionally read news of these mammalian “celebrities” spending time in what could be deemed “unknown territory”, such as the corner store or […]
eBook: Aging and EpigeneticsJune 8, 2018This eBook explores various levels at which aging and epigenetics are related. Assembled are summaries of studies exploring specific questions regarding the epigenetic basis of aging and aging-related conditions. They are divided into four chapters: 1. DNA Methylation Epigenetic Clock 2. Anti-aging 3. Alzheimer’s Disease 4. Stem Cells
Cognitive Benefits of Dad’s Enriched Environment Passed to Offspring Through Sperm miRNAsMay 25, 2018With Father’s Day just around the corner, it’s the time of year we think about how we can “enrich” Dad’s life with power tools, gift cards, and hand-made crafts. But maybe we should be looking into enriching Dad’s cognitive environment because it turns out that he can pass those benefits on. In mice, the environmental […]
Keeping it CLASSY with RNA-directed DNA Methylation in ArabidopsisMay 22, 2018There’s many ways to keep it classy, and while the recent Royal Wedding has demonstrated that some families illustrate their style with an eclectic taste for hats and fascinators, the CLASSY family of chromatin remodeling factors has just out-classed them with its chromatin tastes that shape RNA-directed DNA methylation. In Arabidopsis thaliana, RNA Pol-IV triggers […]
