Sea Snails Thank RNA-induced DNA Methylation for the Long-term Memories!May 16, 2018Forget everything you know about memories (!) because a new study has turned our knowledge regarding memory formation on its head by showing the ability to transfer memories from animal-to-animal! Current dogma states that learning-induced modifications of synaptic connections underlie the storage of our long-term memory (LTM); however, recent studies have suggested that neuron cell […]
C. elegans Histone Memory of a Tropical VacationMay 14, 2018Most of us wouldn’t mind taking a tropical vacation, and we’re all likely to snap a few selfies to capture vacation memories. While the humble Caenorhabditis elegans may lack the latest phone and accompanying selfie stick, it makes up for it with epigenetic memory of warm weather vacations. More specifically, worms raised at higher temperatures undergo […]
Snord116 Keeps DNA Methylation’s Circadian Rhythm Ticking in the BrainMay 10, 2018Sunrise, Sunset. The tempo of a day can quickly pass us by while filling our brain with all epigenetics has to offer. But whether our brains are aware of it or not, with each sunrise and sunset comes a rhythmic genome-wide DNA methylation profile. To gain insight into exactly what makes our brain’s rhythmically tick, […]
EpiTOF Histone Modification Analysis Reveals How Aging Cells Grow Apart!May 9, 2018Some say that all babies look the same – small, warm bags of tears and mayhem – with significant differences only appearing as we grow older and grow apart from our newborn brethren (and sistren!). Our burgeoning epigenome may react to aging in a very similar manner, with age-related losses and gains of DNA methylation combining […]
Two Barcodes, One DNA Fragment: Budget-Friendly Single-Cell Whole-Genome Bisulfite SequencingApril 29, 2018While single-cell whole-genome bisulfite sequencing is rapidly evolving, the associated price tag hasn’t been quite as dynamic. This lack of dynamism is primarily because current single-cell whole-genome bisulfite sequencing (scWGBS) methods are limited by the need to process each cell in individual reaction vessels and also low alignment rates. These limitations mean a high (financial) […]
