Sometimes, when you’re dealt the right hand, doubling down is a sound strategy. Although it can be a risky move in blackjack, a new ChIP-seq method makes it a sure thing when you’re dealing with bivalent chromatin. The strategy, which includes important preparation steps and two rounds of chromatin immunoprecipitation (ChIP), provides sensitive genome-wide profiles […]
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Search Results for: ChIP
Webinar: Chromatin Immunoprecipitation (ChIP) Workshop – Dr. Toryn Poolman
If you’re new to chromatin immunoprecipitation (ChIP), or you’re thinking about giving it a try, you will want to take the time to watch this webinar first! Our friends at Proteintech put together an excellent workshop led by Dr. Toryn Poolman at University College London that covers a ton of tips and tricks that will […]
Like a RedChIP to a Bull! – New Technique Explores RNA-Protein-DNA Interactions
The publication of a new technique is like waving a red rag to a bull for many in the epigenetics arena. Now, “RedChIP” has us stampeding in anticipation towards the exploration of the complex interactions taking place between RNA, DNA, and proteins in the nucleus. Olé! Non-coding RNAs (ncRNAs) interact with proteins and DNA to […]
Paired-Tag Pairs Up ChIP-Seq and RNA-Seq for Single-Cell Multiomics
With Valentines day just behind us, a new genome-wide assay has reinforced the perks of pairing up for single-cells. While multiomic methods have been gaining momentum, it has been tricky for researchers to play matchmaker with ChIP-seq at the single-cell level. To meet this challenge, the lab of Bing Ren at the University of California […]
rChIP-Seq Ratifies RNA as a Requirement for PRC2 to Rock and Roll
Once in a while, an epigenetic technique comes along to rock your world more than your favorite Led Zeppelin or Foo Fighters album! Now, a band of researchers fronted by the dynamic duo of John L. Rinn and Thomas R. Cech (University of Colorado, Boulder, CO, USA) has just released a chart-topping masterpiece with their […]