Bacteria, viruses, and fungi in the mammalian gut microbiome vastly outnumber the cells in the human body; however, the detailed mechanisms these gut-dwelling commensal partners use to communicate with their generous hosts and induce responses represent somewhat of a “missing link” in this research. Now, a new epigenetics-based study shows that we should have been […]
- "lncRNA"
Search Results for: lncRNA
A Novel lncRNA Plays Cat and MAOs with Aggressive Behaviors
It’s the classic dilemma — do you eat that delectable morsel of cheese now or save it for later? If you tend to lack self-control, you might be at higher risk of impulsive or aggressive behavioral disorders, which have been linked to genes in the monoamine oxidase (MAO) family. A new study from the lab […]
HiChIRP-y New Protocol Reveals the Scaffolding Function of lncRNAs
Freshly brewed coffee, a lightly toasted bagel, the sweetness of orange juice; what makes you feel “chirpy” first thing in the morning? The good people from the labs of William J. Greenleaf and Howard Y. Chang (Stanford University, CA, USA) have been waking up, working hard, and feeling good, all thanks to the development of […]
Giving Identity to the Masses: Antisense lncRNA Transcription Facilitates DNA Demethylation to Determine Promoter Choice
As modern technology develops, we grow increasingly connected with one another while also striving to maintain our individual identities. Although some may blame social media for our desire to be unique snowflakes just like everyone else, exciting new research demonstrates a molecular mechanism for individual neuronal identity in the brain that may just be the […]
LncRNA-mediated Trisomy Silencing: Is the Reversal of Down Syndrome-associated Disease Just an Epigenetic Switch Away?
While “the rule of three” principle may make three the magic number for fairy tales and Hollywood blockbusters, trisomy of chromosome 21 causes Down syndrome (DS) and leads to the development of a range of severe associated disease and disorders in affected patients. However, research out of the laboratory of Jeanne B. Lawrence (University of […]