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Epigenetics and ncRNA Headlines

Get all the latest highlights from the literature and special features covering trending epigenetics, ncRNA, and gene regulation research.

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An Eerie Epigenetic Disguise Helps SARS-CoV-2 Avoid Anti-viral Responses

October 25, 2022

Every avid trick-or-treater aspires to have the perfect Halloween costume; now, a spooky study has revealed how an unwanted guest – SARS-CoV-2 – dons an epigenetic disguise to help this virus trick its way past host defenses to infect human cells! A fearless team led by Erica Korb (University of Pennsylvania, USA) knew that SARS-CoV-2 […]

RT&Tag Maps the Fleeting World of Chromatin-associated RNAs

October 25, 2022

Between the vast lands of DNA and proteins lies the ephemeral and dynamic world of chromatin-associated RNAs, a less-explored but utterly critical domain of the eukaryotic nucleus. Thankfully, RNA-focused researchers can now turn to a tagmentation-based profiling technique (“RT&Tag”) to map the landscape of regulatory chromatin-associated RNAs to aid this quest. In their fascinating study, […]

Single-Cell Spatial and Multimodal Upgrades to ATAC-Seq Speed Up Your Chromatin Insights

October 9, 2022

Need to get swiftly up to date with recent advances to the assay for transposase-accessible chromatin with high-throughput sequencing (ATAC-Seq) technique? Well, slow down and read on for the latest single-cell spatial and multimodal updates to your chromatin toolbox! Our first study gives us a quick lowdown on Spatial-ATAC-seq, a technique to capture spatial chromatin […]

Placental Proxies: A Shared DNA Methylation Profile Between cffDNA and Brain

September 27, 2022

When you’re looking to access the latest and greatest publications, your VPN is the proxy you need. But now, there’s a new proxy in town to help with your quest for neurodevelopmental epigenetic information: Placenta and the cell free fetal DNA (cffDNA) that originates from it. A dynamic duo of papers from the lab of Janine LaSalle (UC Davis […]

RNA Methylation and DNA Demethylation Teamwork Make the Transcriptional Dream Work

September 25, 2022

Dream teams come in all shapes and sizes, from the 1970 Brazil football team to the Mercedes F1 team of the 2010s. A new epigenetic alliance formed between RNA methylation and DNA demethylation recently made its competitive debut and now shows how teamwork makes the dream work! A synergistic team led by Dongxin Lin, Jian […]

Brain Cells Choose Cilia Over Social Media to Make Exciting New Connections!

September 19, 2022

When was the last time you made an exciting new connection? At an international conference, the coffee shop, or social media? A welcoming new study now provides evidence that brain cells don’t go to these lengths or even have to take a standard synaptic approach; instead, they use a connection – an axo-ciliary synapse – […]

Keeping Aging in LINE by Stabilizing Heterochromatin

September 11, 2022

Like many aspects of our lives, epigenetic processes can get out of control during aging. Now, exciting new findings have revealed that the secret to keeping our aging epigenomes “in line” is removing LINE-1 RNA from cells, which stabilizes heterochromatin and reverses signs of aging! Previous studies have shown how age-associated heterochromatin loss associates with […]

Multiomic Face-off Finds the Factors that Lead to Look-alikes!

September 6, 2022

Have you ever heard of someone bumping into their doppelgänger and wondered how the forces of biology conspired to make two unrelated people look alike? In a recent study, a few familiar faces took advantage of a photographer’s keen eye and a multiomic “face-off” to find those factors that lead two strangers to look alike! […]

eBook: Single-cell Methods in Epigenetics and Genomics

August 24, 2022

Single-Cell methodologies can be the most comprehensive way to identify cell subpopulations with different transcriptome and epigenetic profiles within complex samples, eliminating the need for isolation strategies like FACS or magnetic sorting that could alter the biology due to sample manipulation. These methods are proving to be invaluable for Identifying novel cells that modulate response […]

Novel Multiomic Epigenetic Clock May Decipher How Epigenetic Aging Impacts Cell Function

August 23, 2022

Timely advances have demonstrated that significant changes to DNA methylation levels accompany the creaking knees, failing eyes, and changing tastes in music (!) associated with the human aging process. A well-timed study now builds upon these past studies to describe a multiomic-based approach with the potential to forge links between epigenetic aging and the gene […]

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Epigenetics and ncRNA Headlines

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