Chromatin research keeps blowing up right along with the rest of the epigenetics field over the last six months or so of 2010. Here are some of our favorite Chromatin headlines covering things like chromatin remodeling, transcription ehancers, histone turnover and nucleosome positioning.
The dynamics of nucleosome interactions and displacement during cellular processes still remain a bit of a black box, so we pounce on any good pubs that make this arena less hazy.
October 26, 2010. Chromatin Remodelers In Search of Mr. Right
This piece, contributed by Dr. Istvan Ladunga tackled an ongoing debate on nucleosome stability. His team determined that the source of much of the conflicting data out there is caused by movable, or “fuzzy”, nucleosome positioning.
November 5, 2010. Nucleosome Positions Are Cloudy With Chance of Stability
This team ushered in a new approach to get at the core of histone turnover and how turnover rates are influenced by site-specific, post translational mods and sequence variants.
December 15, 2010. SILAC Offers a New Twist on Histone Turnover
It seems like every day we get junk mail about “enhancers,” so it was nice to see this great pub tackled the enhancers that we really care about. This research team took a close look at these mysterious regulatory elements and found H3K27ac could predict enhancer activity.
December 1, 2010. H3K27ac Marks the Spot of Active Enhancers
We love it when we find nice publications tackling the transcriptional love triangle with DNA methylation and histone marks.
November 30, 2010. Behind the Scenes Histone and DNA Methylation Regulation Tricks Revealed