It has become apparent over the last decade that small and long noncoding RNAs play a major role in the regulation of gene expression and disease. While much emphasis has been centered on the role of noncoding RNAs in human disease, a gap remains in utilizing this knowledge to develop target specific approaches to disrupting noncoding RNA pathways for therapeutic gain. This meeting will for the first time bring together an interdisciplinary group of basic and applied noncoding RNA scientists in an effort to translate our current understanding of noncoding RNA biology into meaningful therapeutics for many of those diseases afflicting society. To accomplish this goal, the meeting will aim to: (1) Introduce the broad genome-wide basic fabric of noncoding RNA regulation and form and function in the cell; (2) Focus on direct RNA/chromatin/DNA or RNA/protein interactions with candidate disease-relevant model systems; and (3) Highlight synthetic biological approaches to developing RNA or oligonucleotide mimics to target and/or disrupt particular disease-relevant noncoding RNA pathways. The goal of this meeting is to bring together basic and applied scientists working on noncoding RNAs in an effort to not only better understand the role noncoding RNAs play in the regulation of disease-relevant genes but also the emerging ability to utilize this knowledge to develop targeted therapeutics, an eventuality that heralds a new frontier in drug development and therapeutics.
- Conferences
- Noncoding RNAs: From Disease to Targeted Therapeutics
Noncoding RNAs: From Disease to Targeted Therapeutics
Keystone Symposia - 05 Feb 2017
Summary
Topics
Details
Meeting Summary
Topics Include
- Disease Specific Noncoding RNAs: From Complex Genomic Interactions to Mechanism
- Molecular Mechanisms and Functional Studies of Protein Interactions with Non-Coding RNAs in Disease
- Molecular Mechanisms of ncRNA Protein Interactions in Disease
- Nucleic Acid Based Strategies to Disrupt ncRNA and Gene Interactions
- RNA and DNA Control of Genes and Gene Networks in Disease
- Synthetic RNAs, from Evolution to Catalysis to Functional Gene Targeting
- Therapeutic Approaches to Disrupting or Mimicking lncRNA Function
Meeting Details
Date | 05 Feb 2017 |
Location | Fairmont Banff Springs Banff, Alberta, Canada Get Directions |
Organizers | Kevin V. Morris, Archa Fox and Paloma Hoban Giangrande |