We’re halfway through 2010, so we’ve decided to take a look back at some of the best epigenetics publications we’ve covered so far this year. Here are some of our favorite DNA Methylation headlines.
If your methylation profiles have been looking a little fuzzy, it could be CpG-SNPs are to blame. CpG-SNPs where found to be involved with in allele-specific methylation, or they might cause “fuzzy methylation”, which is why this article was a favorite.
Stem Cell Reprogramming
Borrowing a page from zygotes, researchers hope that by adding Elp3, a protein critical to demethylation of the paternal genome, to their “reprogramming cocktails”, they’ll be better able to create stem cells with a clean methylation slate.
January 6, 2010 Zygotes Reboot On Paternal Methylation Patterns
Thanks for the memories, DNA methylation. Hypermethylation of certain genes was shown to help lock memories into long term storage, and give us a peek into the molecular inner-workings of memory formation.
June 7, 2010 Memories Saved By DNA Methylation
Nucleosome/DNA Methylation Interaction
We’ve been seeing a lot of action on nucleosomes lately, and this paper goes a long way toward sorting out their relationship with DNA methylation.
June 7, 2010 Unscrambling Nucleosome-DNA Methylation Relations