News reports tell us how tough the job market is lately, so we’re doing our part for the global economy by posting these two new epigenetic research positions that the Ontario Cancer Institute (OCI) is looking to fill. Who knows? Maybe one of them is perfect for you.
Postdoctoral Research Fellow or Research Associates – Cancer Epigenetics
OCI at Princess Margaret Hospital – a teaching hospital of the University of Toronto – ranks in the top 5 cancer research centers in the world. Its research activities are concentrated on epigenomics, cancer immunotherapy, cancer stem cells, image-guided therapeutics, patient survivorship, and personalized medicine. The University of Toronto and its affiliated hospital research institutes comprise one of the largest and most productive centers of biomedical research in North America. For more information about the institute: http://www.uhntrainees.ca/
Two postdoctoral Fellow or Research Associate positions are available immediately within the group of Daniel D. De Carvalho, Ph.D
- Computational Biology – The De Carvalho lab focuses on understanding the mechanisms driving cancer-specific epigenetic alterations, with the ultimate goal of allowing target-specific epigenetic interventions. To achieve this goal, they perform functional genomic screening, combined with systems biology and a variety of genome-wide profiling of epigenetic modifications, using next-generation sequencing (NGS) and microarray technologies. They are specifically seeking individuals with strong computational, bioinformatics, and/or statistical backgrounds to be involved in NGS data analysis. Applicants must be highly motivated and able to communicate effectively in English.
- Molecular Biology/Immunology – The De Carvalho groups also seeks individuals with a solid background in Molecular biology and/or immunology to lead the investigation into the mechanisms of epigenetic therapy as a primer for cancer immune-therapy. Applicants must be familiar with some of the following techniques: quantitative qPCR, mammalian cell culture, cloning, RNAi, shRNA library, ChIP, western blot, flow cytometry and luminex. Applicants must be highly motivated and able to communicate effectively in English.
You are encouraged to brush up on the labs precious work in the following papers:
- Cancer Cell. 2012 May 25;21(5):655-67 (PMID: 22624715)
- Cell. 2011 Dec 9;147(6):1283-94 (PMID: 22153073)
- PNAS. 2011 Aug 30;108(35):14497-502 (PMID: 21844352)
- PLoS Genet. 2011 Feb 3;7(2):e1001286 (PMID: 21304883)
- Nat Biotechnol. 2010 Oct 13;28(10):1069- 1078 (PMID: 20944599)
- Oncogene. 2011 Jan 13;30(2):223-33 (PMID: 20838376)
If you think you’d make a good fit, send your curriculum vitae and the contact information for 3 references to Daniel D. De Carvalho, Ph.D. (ddecarv@uhnresearch.ca).