Eyesight from the Blind: DNA Methylation Causes Cavefish Eye DegenerationJune 11, 2018While we are no strangers to the role of epigenetics in environmental adaption, the lab of Brant Weinstein at the National Institute of Health (Maryland, USA) has brought forth an example of environmental adaption so extreme that it provides profound insight into eye degeneration and blindness. The talented team chose to examine the Mexican tetra […]
SPRITE: A Refreshing New Approach for Identifying Higher-Order Genomic StructureJune 11, 2018Are you looking for a refreshing new nuclear organization assay this summer? Well look no further than SPRITE, it will quench your thirst for a better DNA conformation assay. There are a lot of methods for assessing higher-order DNA structure, but they mostly fall into two categories: proximity ligation and in situ imaging. Proximity ligation […]
Mammalian MicroRNA Travels into the Unknown Territory of the Nucleus to Epigenetically Silence Gene ExpressionJune 9, 2018While we are accustomed to seeing soccer players stroking a ball up and down grassy white-lined pitches and actors waltzing down the red carpet wearing a sharp suit or a stunning dress, we occasionally read news of these mammalian “celebrities” spending time in what could be deemed “unknown territory”, such as the corner store or […]
eBook: Aging and EpigeneticsJune 8, 2018This eBook explores various levels at which aging and epigenetics are related. Assembled are summaries of studies exploring specific questions regarding the epigenetic basis of aging and aging-related conditions. They are divided into four chapters: 1. DNA Methylation Epigenetic Clock 2. Anti-aging 3. Alzheimer’s Disease 4. Stem Cells
Elegant C. elegans Study “Drops” in to Show How Liquid Droplet Formation Mediates Epigenetic InheritanceMay 28, 2018While some studies may appear as drops in the scientific ocean, a drop-dead gorgeous paper on epigenetic inheritance recently made us all drop our guard! Although studies have established transgenerational epigenetic inheritance (TEI) across several generations in the nematode worm Caenorhabditis elegans and the critical role of non-coding RNAs, we have yet to unravel the […]
