Get Tissue-Specific with EMD Millipore’s CpGenome™ 5-hmC Quantitation KitDecember 26, 2012One of the few things epigenetics researchers know for sure about 5-hmC, is that it’s highly variable amongst different types of tissues and cell types. So where does your favorite sample fall on the 5-hmC quantity spectrum? Thanks to the new CpGenomeTM 5-hmC Quantitation Kit from EMD Millipore that question is easier than ever to […]
EMdeCODE Deciphers Epigenetic Code, Finds New Role for Old Histone ModificationsDecember 19, 2012With all the “LOL”s, “IMHO”s, and “YOLO”s out there, it’s like we’re all speaking in code. When we get stumped on what these things mean, we can always turn to Google. But what if you want to decipher the hypothetical “epigenetic code?” Well, one researcher has the answer—EMdeCODE, a new algorithm that does just that […]
Hypermethylation in miRNA 26a Provides New Route in Prostate Cancer ProgressionDecember 12, 2012There’s usually more than one right way to get where you want to go. Unless of course, you’re using Apple Maps, then all routes are questionable, but at least have a pretty interface. It turns out there are at least two ways to wind up with prostate cancer, and neither are that attractive—having a gene […]
5hmC Analysis TimelineDecember 10, 2012EpiGenie has probably covered developments in 5hmC more than any topic the last couple of years, so we’ve compiled this timeline for you. Scroll along to see what you may have missed if you’ve been out of the loop or lab for a sabbatical.
New and Improved: Multiplexed Reduced Representation Bisulfite Sequencing (RRBS)December 7, 2012These days, we’re all about multi-tasking—talking on our cell phones while placing our cappuccino order at Starbucks and tweeting about it all on our tablets. In that same vein, researchers report an optimized protocol for multi-tasking (well, technically “multiplexing”) reduced representation bisulfite sequencing (RRBS) for ramped-up DNA methylation data. RRBS is great, churning out methylation […]