Could there BE anymore genes affecting DNA methylation? Actually, yes! We always hear about the main cast of the methylation show, the DNMTs and the TETs, but where are all the supporting actors that attract, repel or otherwise interact with these stars? A new show (study) from the studio (lab) of Bastiaan Heijmans (Leiden University […]
Epigenetics and ncRNA Headlines
Get all the latest highlights from the literature and special features covering trending epigenetics, ncRNA, and gene regulation research.
While a “bird’s-eye view” of a topic can often provide colossal insight, the opposite perspective can sometimes be just as useful! Recently, two fascinating studies of transgenerational epigenetic inheritance have taken a “worm’s-eye view” of this research area to deepen our understanding of this complex mechanism in the model nematode worm C. elegans. C. elegans […]
It takes real restraint to prevent a routine hedge trim from turning into a horticultural horror show; and like an overzealous landscaper, new research shows that TET2 may be mowing down the methylome in Parkinson’s Disease (PD) neurons. The cognitive and motor symptoms of PD are caused by the degeneration of dopamine-producing neurons in the […]
Away with you Holmes, begone Poirot, and bye-bye Nancy Drew, because a terrific team of epigenetic detectives has solved an epitranscriptomic cold case to reveal the “Y” of aggressive colon tumors by linking CpG island promoter DNA hypermethylation of a key epitranscriptomic modifier and a transfer RNA (tRNA) modification to tumorigenesis. Epitranscriptomics includes the modification […]
Move over, Rogaine; the pharmacies of the future will carry hair regrowth treatments that contain microRNAs from hair follicle exosomes! There are creams, supplements, lasers and even surgery, but people struggling with hair loss still don’t have a convenient and effective treatment to help them restore their luscious locks. New treatments could involve injecting dermal […]