Our signatures are unique marks that let people know where we’ve been. It turns out that epigenetic modifiers leave their own signatures on the genome. There are between 300-400 proteins that regulate the epigenome, including readers, writers, & erasers of histone marks as well as chromatin remodelers. Genetic variants in the epigenes that encode these […]
Epigenetics and ncRNA Headlines
Get all the latest highlights from the literature and special features covering trending epigenetics, ncRNA, and gene regulation research.
While the above title may conjure up images of Star Wars-esque galactic battles, the epic clash between the LINE-1 (L1) retrotransposon and repressive forces takes place on the scale of microns instead. This war has been waging in the human genome for thousands of years: L1 attempts to replicate and integrate into the genome, while […]
Have you ever run into an unexpected detour on your commute? Whether it be an ice patch, flood, or even a mudslide, mother nature can reroute even the best laid plans, but for some species, changes in the environment have much higher stakes than being late for work or that much needed vacation. In fact, […]
The appreciation of the mitochondrion as “the powerhouse of the cell” has become as culturally pervasive as some of our favorite memes; however, a powerful new study now shows that signals deriving from this double-membrane-bound ATP-generating organelle represent a major driving force behind alterations to the epigenome. A talented team of researchers from the lab […]
Some families have heirlooms that get passed down from generation to generation but if you’re a nematode, you might inherit more than just your Grandpa’s pocket watch! The phenomenon of transgenerational epigenetic inheritance (TEI) was first discovered in Caenorhabditis elegans, where environmental stressors can alter physiological responses in offspring up to 20 generations later! Since […]