Become a ChIP Assay Expert! The chromatin immunoprecipitation (ChIP) assay is one of the best ways to study the association of DNA-binding proteins with chromatin and the localization of histone modifications throughout the genome. But ChIP assays take time to master. Our friends at Active Motif have put together this free ChIP 101 eBook that […]
Keeping up with the rapidly evolving technology landscape for epigenetics and non-coding RNA research can be daunting. Learn more about the available methods out there and stay on top of the latest developments in our Technology section.
When it comes to love, being single has its pros and cons. This is also true for cells, single cells give a lot high-resolution picture, but it’s often very difficult to get enough material. While other single cell methods have flourished with low inputs, studies of the heterogeneity of chromatin states by single cell chromatin […]
While trying to uncover the mysteries of the DNA methylation, a lot of BS is often required. And no, we’re not talking about workplace politics but rather sodium bisulfite (BS) conversion. Thankfully, the labs of Chun-Xiao Song and Benjamin Schuster-Böckler at Oxford University (UK) have developed a new “BS-free” approach to uncover the secrets of the […]
Every population has its own unique identity, and behind that is our brain, an organ composed of cellular populations with their own unique DNA methylation identities. However, capturing the true diversity of a population requires the ability to observe each individual in that group and for methylomes that requires innovations in single-cell bisulfite sequencing. In […]
They help organize our schedules, they keep us in touch with good (and bad) friends, and they barely leave our sides throughout the day. But can we exploit the ubiquitous nature of smartphones to facilitate personalized treatment of human disease? This is the hope of researchers from the laboratory of Haifeng Ye (East China Normal […]