From Greta Thunberg leading global climate protests to Katie Bouman capturing the first picture of a black hole; sometimes an emerging star can create enormous waves on the world scene. In the realm of epigenetics, the “humble” N 7-methylguanosine (m7G) modification forms the eukaryotic mRNA cap, a structure that regulates mRNA export, translation, and splicing, […]
EpiGenie Features call out new Methods, provide Insights into emerging trends, or sometimes just share technical tips from the experts in our community.
It takes a special kind of small RNA to try out for the PIWI team. PIWI-interacting RNAs (piRNA) are small, have and adenine at their 10th position, an uracil at their 5’ end, and 2’-O-methylation at their 3’ end. This unique physique helps piRNA work with PIWI proteins to defend the germline against an aggressive transposon offense, but […]
Many people make dubious claims of being endowed with more than the five traditionally recognized senses; their “sixth sense” providing the extrasensory perception needed to converse with spirits and ghosts and predict the future, among other fanciful claims. While there is a lack of any evidence for extrasensory powers and paranormal activity, robust studies have […]
There aren’t many studies exciting enough to make you jump out your lab coat and rock’n’roll round the lab like it’s the 50s, but a recently reported new application of CRISPR might just start your toes tapping and your heads nodding. This new article does not originate from “Deep down in Louisiana close to New […]
Little-by-little, step-by-step, and drop-by-drop, we are beginning to appreciate the vital importance of intracellular liquid-like droplet formation to fundamental mechanisms such as epigenetic inheritance and heterochromatin domain formation. Liquid-like droplets aid these processes by biological “phase-separation” or the selective concentration of some molecules into a small intracellular area and the exclusion of others. Excitingly, two new […]