Features

Features

EpiGenie Features call out new Methods, provide Insights into emerging trends, or sometimes just share technical tips from the experts in our community.

Search Articles

The Brain Cell Census: A Deeper Epigenomic Understanding of the Mammalian Mainframe

November 13, 2023

If you have epigenetics on the brain like us, concentrate your mammalian mainframe on the recently published marvels on the brain’s epigenome from the NIH’s Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative – Cell Census Network (BICCN). Recent work brought together under the guise of the Brain Cell Census now reports on the examination […]

Kacme: A New Histone Modification Couples Methylation and Acetylation to Mark Active Transcription

October 23, 2023

Some couples seem unlikely, yet somehow, they work (a recent pop star-football player pair comes to mind). Now, an even more surprising couple—a methyl group and an acetyl group—hanging out together on the very same lysine residues on histone H4s has just been spotted across species and appears to be involved in active transcription. Mind. […]

eBook: RNA & Transcriptomics

October 13, 2023

Analysis of the working of our RNA, from transcription and splicing to translation, began in a simpler time – when we talked about “RNA” and hadn’t yet recognized the whole range of RNA species, including miRNAs, ncRNAs, and more. These days, we are learning as much about the epigenetic modification of RNA and the role […]

Epigenetic Inheritance During DNA Replication: A State Lying Somewhere Between Symmetry and Instability

October 2, 2023

Emerging research has provided evidence for the critical importance of the inheritance of epigenetic states, whether that be DNA methylation, histone modifications, or even non-coding RNAs. Now, three recent studies focusing on the mechanism involved in passing down this information from parental to daughter cells while they replicate their DNA and divide in vitro provide […]

Just Add HiDRO to Figure Out How Genomes Fold in Single Cells

September 14, 2023

Water hydrates and is essential for life—for plants, humans, and even fish. So, it’s fitting that a new technique called HiDRO takes high-throughput FISH to the next level to identify factors that help genomes fold in 3D at high throughput in single cells. Cohesin helps DNA form loops, which can then form topologically associated domains (TADs). […]

An Evolutionary and Epigenetic Tour-de-force Links DNA Methylation and Mammalian Aging

September 11, 2023

Have you climbed Mount Everest? Recorded a critically acclaimed album?? Written the great American novel??? These life-affirming feats of body and mind pale into insignificance when compared to the evolutionary and epigenetic tour-de-force reported in two recent papers based on mammalian DNA methylation datasets of colossal size and importance. An expeditionary force led by Steve […]

eBook: Chromatin & Gene Expression

June 14, 2023

Gene expression is regulated by a range of factors, but ultimately begins with chromatin – it’s structure, configuration, activation, and “openness”. All of these factors can be dynamically regulated by epigenetics. In this eBook, we bring to your attention some of the most interesting articles in chromatin biology and gene expression, from practical methods to […]

Gene Topology or Gene Expression? NSD1 Chooses Both to Protect the Brain

May 23, 2023

We have to make a lot of decisions in our lives, but sometimes when given two choices, going with both can be the right answer. For example, researchers working on neurodevelopment figured out two different phenomena that regulate non-CG methylation in the postnatal brain, but how are they connected? Now, Harrison Gabel’s lab (Washington University […]

BIND&MODIFY and NOMe-HiC Go the Distance with Single-Molecule, Long-Range Epigenetic Maps

May 4, 2023

Staying in your own neighborhood can be nice, but sometimes you need to go on a trip and see different scenery. Chromatin is a lot like that—things can look very different along a DNA strand that bends and folds. That’s why two separate teams have come up with multi-omics methods that go the whole distance […]

eBook: Epigenetics of Cancer & Disease Risk

May 3, 2023

The application of epigenetic approaches to disease research is moving quickly and hundreds of new papers are published every year, from virology to neurobiology and cancer. In this eBook, we present short summaries of interesting discoveries that caught our attention in each of these areas. Table of Contents Chapter 1: Epigenetics in Disease Risk Taking […]

Pages: 12345678910111213141516171819202122232425262728293031

TAP

Features

Featured Articles

Search Articles