With as many flavors as there are epigenetic modifications, vaping has arrived on the scene as a safer alternative to the smoking of cigarettes and a means to give up a rather unhealthy habit. However, the rise in vaping-related lung injuries and the “unforeseen” massive uptake of vaping by teenagers have prompted scientists to undertake […]
- Cancer Epigenetics
Biotechnology Development and Cancer Epigenomics with Dr. Martin Hirst
Dr. Martin Hirst from the University of British Columbia discusses his lab’s epigenomic research focused on biotechnology development and cancer at the 2019 joint CEEHRC/IHEC meeting.
Deciphering the Warburg Effect: The Metabolic By-product Lactate Modifies Histones
Like the energy drink cans and protein bar wrappers that litter the table after an epic writing session, by-products generally represent undesirable items created during the generation of a more desirable object. Recycling can put some writing by-products to further use, and studies have now highlighted that biological by-products derived from cellular metabolism can also […]
Mutant DNMT3A Underperforms in Overgrowth Syndrome
If you’re underperforming at work, you might end up with a rejected paper, failed experiments, or an angry boss. However, this isn’t so bad when compared to how mutated DNMT3A underperforms in its role as a DNA methyltransferase, since that can result in a pathogenic overgrowth known as Tatton-Brown-Rahman syndrome (TBRS). Despite DNMT3A’s known role […]
Heterochromatin Finds an Alternative Way to Lengthen Telomeres
We recently advised our readers to “think different” when it came to the epigenetic control of maintenance in alternative lengthening of telomeres (ALT) cells, and now, a team of “out-of-the-box” thinkers from the lab of Jérôme Déjardin (Université de Montpellier, France) have described an unconventional link between ALT and telomeric heterochromatin formation. Previous results have […]