Want to detect the development of pancreatic cancer and improve patient outcomes but don’t have any tissue biopsies? An exciting new epigenetics study that employed liquid biopsies to detect 5-hydroxymethylcytosine (5-hmC) on circulating cell-free DNA (cfDNA) to allow the early detection of pancreatic cancer now says: “No Problem!” Researchers at Bluestar Genomics (San Diego, CA, USA), […]
- Cancer Epigenetics
Away with you Holmes, begone Poirot, and bye-bye Nancy Drew, because a terrific team of epigenetic detectives has solved an epitranscriptomic cold case to reveal the “Y” of aggressive colon tumors by linking CpG island promoter DNA hypermethylation of a key epitranscriptomic modifier and a transfer RNA (tRNA) modification to tumorigenesis. Epitranscriptomics includes the modification […]
Finding the cell free DNA (cfDNA) that most cell-types release into blood plasma is always a challenging task, but certain cancers release so little that it takes looking for a needle in a haystack to the next level. Methods for sorting the “hay” have often come up short, but two new studies successfully developed a […]
With as many flavors as there are epigenetic modifications, vaping has arrived on the scene as a safer alternative to the smoking of cigarettes and a means to give up a rather unhealthy habit. However, the rise in vaping-related lung injuries and the “unforeseen” massive uptake of vaping by teenagers have prompted scientists to undertake […]
Dr. Martin Hirst from the University of British Columbia discusses his lab’s epigenomic research focused on biotechnology development and cancer at the 2019 joint CEEHRC/IHEC meeting.