A Great Start to RNA-Seq: Zymo Research’s RNA Clean & Concentrator™-5July 1, 2013With every high-tech advance in the methods used for RNA analysis , the need for extremely pure RNA input samples becomes even more crucial. The RNA Clean & Concentrator™-5 (RCC™-5) Kit from Zymo Research packs high-performance into a fast and easy format that enables even the most demanding methods, including RNA-Seq. RNA Clean and Concentrator™-5 […]
The Darkside of Epigenetic PlasticityJune 26, 2013Sure, genes get mutated in cancers, but the epigenome gets messed-up too. In fact, two researchers argue in a recent review that a “dysregulated epigenome” that’s too plastic and flexible could itself lead to cancer. Andrew Feinberg and Winston Timp, both from the Center for Epigenetics at the Johns Hopkins School of Medicine, wrote the […]
Webinar: Lighting up the Dark Matter of the Genome – Unravelling the Roles of Non-Coding DNA in Disease and DevelopmentJune 26, 2013Dr. Marcel Dinger, PhD discusses some of the most recent findings that shed light on non-coding RNAs in the genome. **this webinar is no longer available** Abstract Approximately 98% of the human genome comprises noncoding DNA, the function of which is largely unknown. Intriguingly, more than 85% of single nucleotide polymorphisms identified to be associated […]
Keeping Up with Live Cell DNA LoopingJune 25, 2013The reality TV era has made voyeurs of us all. So it makes sense that we’d want to take a peek inside live cells too. Now comes a report of a new method that shows, for the first time, DNA getting loopy inside live E. coli cells. Johns Hopkins University Med School researchers say that […]
DeepSAGE Digs up Expression Differences in 3’ EndsJune 24, 2013It isn’t always a good thing to get the end of something, but researchers say that by grabbing onto 3’ ends of transcripts and tagging them, DeepSAGE digs deep, getting low-level transcripts and getting new info on their “back-ends.” That could be important for figuring out exactly how gene expression changes with disease. “It was […]