Synthetic Biology News

Synthetic Biology Headlines

Get all the latest highlights from the literature and special features covering trending synthetic biology research and applications.

Search Articles

“Epi-bit” Encoded Images of Tigers and Pandas Reveal the Epigenetic Future of DNA-based Memory Storage

November 10, 2024

A memorable musical number from Cats muses on the loss of “Memory;” however, an unforgettable new feline-related study now describes the encoding of images of tigers (and pandas!) using printed epigenetic bits (“epi-bits”) on DNA as a novel storage approach for our data and dearest recollections. Can epi-bits make any memory loss a thing of […]

eBook: CRISPR & Gene Editing 2024

October 17, 2024

CRISPR/Cas-mediated gene editing represents a straightforward and accurate process; however, the widespread therapeutic application of this technology still requires the precise characterization of both on- and off-target activity. In this eBook, we highlight a recent group of publications and methods using this powerful technique! Contents: Epigenetic Machinery Fights Back! SARS-CoV-2 RNA Modifications Inhibit Replication and […]

An Oliver’s Twist on an Old Tale: Orphan CpGs Will Have You Asking for More

July 17, 2021

Move over Oliver Twist, there’s a new orphan in town to satisfy our hunger for stories of DNA methylation. Two new tales of orphan CpGs help them find a home in our hearts and epigenomes through the application of cutting-edge epigenomics techniques and genetic engineering to embryonic stem cells and neuronal cells. Making the Right Connections: […]

New Single-cell CRISPR Screens “ATAC” Chromatin Accessibility

June 6, 2021

Have you been struggling to agree on a plan of action for your recent epigenetic experiments? Have you been fighting over just what strategy to use to decipher how genetic alterations affect the epigenetic landscape? While we should all follow John and Yoko’s example and try to give peace a chance, you sometimes need to […]

dCas9-dMSK1 Provides the Potent Power of Programmable Histone Phosphorylation

February 20, 2021

Time to move over histone methylation, the potent activating power of programmable histone phosphorylation joins the dCas9 epigenome editing toolbox and shows how it takes histone acetylation along for the ride. A rather active team of researchers led by Isaac B. Hilton (Rice University, Houston, TX, USA) knew that phosphorylation represents one of the most […]

Big Things Come in Small Packages: Nanobodies Enter the Epigenetic Editing Ring

February 4, 2021

While we have seen many contenders for the title of heavyweight champion in the epigenetic editing ring, the adage “big things come in small packages” has taken on a new meaning. Nanobodies, or single-domain antibodies, demonstrate that featherweights can pack an explosive epigenetic editing punch by using their opponents’ momentum against them. Researchers led by […]

EpiGo-KRAB: A New, Live-action Tool to Edit and Visualize Heterochromatin Formation in Living Color

January 26, 2021

Like any live-action remake, vibrant colors are essential for a new epigenetic editing tool that simultaneously introduces H3K9me3 at hundreds of targeted loci while also allowing for HD visualization of the heterochromatic results. Now, let’s meet the stars of this show that were cast by a team led by Hanhui Ma from ShanghaiTech University. H3K9me3 […]

Expand Your Epigenetic Editing Portfolio With Targeted RNA m6A Methyltransferases!

August 4, 2020

For the last few years, DNA has cornered the methylation market as the Apple of epigenome editing tools, but a newly developed CRISPR-Cas13 system has epigenetic investors buying stock in RNA editing! 6-methyladenosine (m6A) is the most abundant RNA modification, and even though we know it’s involved in chromatin accessibility, RNA splicing and repairing damaged […]

Epigenetic Editing with CRISPR Keeps Crops Crisp in Today’s Climate

February 25, 2019

While the crisper drawer of our fridge is the best way to keep our produce fresh, epigenetic editing research now brings forth CRISPR-based manipulation of DNA methylation to keep our crops crisp. This tasty treat comes at you in the form of two new publications from the lab of Steven Jacobsen (UCLA), where the talented team expand […]

dCas9-Suntag-DNMT3A Outshines the Off-Target Effects of Direct dCas9-DNMT3A Fusions

June 25, 2018

While even a technology with a future as bright as epigenome editing can have its cold day in the sun, the Suntag system has just cleared the clouds over a growing pain of epigenetic editing: the global off-target effects of dCas9-DNMT3A direct fusion constructs. To cure our epigenetic editing blues, the lab of Ryan Lister […]

Pages: 12345678910111213141516

TAP

Synthetic Biology Headlines

Featured Articles

Search Articles