The modulation of chromatin structure and function is the basis of epigenetic regulation. The replacement of replication-coupled histones in the nucleosome by histone variants is still one of the least understood aspects of chromatin regulation. Advances in recent years have made clear that histone variants play a pivotal role in development and cancer. We will discuss the latest molecular insights into how histone variants are regulated and how they execute their epigenetic function.
This workshop is the fourth of a focused series on histone variants, and will be the first to be organized in a hybrid format. Given the current health situation affecting travel and our ability to congregate in large numbers, this workshop will consist of 40 in-person participants and 100 additional participants to connect online. These numbers will be revised accordingly if the situation changes. We will adapt the workshop program to make this hybrid format as interactive and intimate as possible for both in-person and virtual participants.