eBook: RNA & Transcriptomics

Analysis of the working of our RNA, from transcription and splicing to translation, began in a simpler time – when we talked about “RNA” and hadn’t yet recognized the whole range of RNA species, including miRNAs, ncRNAs, and more. These days, we are learning as much about the epigenetic modification of RNA and the role this plays in gene regulation.

In this eBook, we look at some the most recent topics in RNA and transcriptomics, which can be fairly “hot methods” based, with an equal amount of biological discovery gained from great techniques!

Table of Contents:

Like a RedChIP to a Bull! – New Technique Explores RNA-Protein-DNA Interactions

Location, Location, Location! – How Site-specific mRNA ac4C Acetylation Impacts Translation.

H3K4 Methylation Loss Makes RNAPII Pause for Thought.

HiRES Lets You See Chromatin Structure and Transcription Clearly—At the Same Time

Dnmt3bas Is Inactive Dnmt3b’s Nemesis, Keeping Its Levels Low via Transcription and Splicing.

X Chromosome vs. Autosome – m6A Helps to Level the RNA Stability Playing Field.

Single-cell Epitranscriptomic Mapping of m6A from Small Samples with picoMeRIP-seq.

Let It Rain: Droplets Generate Single-Nuclei Multiomes of Either Histone or RNA Modifications