What do you get when you pair up bisulfite conversion with custom SureSelect™ DNA Capture Arrays? Answers of course, in the form of site-specific methylation data for tens of thousands of CpG sites. For years, adjectives like “high-resolution” and “genome-wide” have been on the wish list of epigenetics researchers keen on tackling the complexities of DNA methylation in larger genomes. Now, combing through methylation patterns almost anywhere in your favorite genome is as easy as subtracting (regions of interest that is). Using custom SureSelect™ DNA Capture Arrays from Agilent, researchers can now capture bisulfite-converted regions of interest and enrich for them before deep sequencing.
Customized target capture designs are limited only by researchers’ imaginations. Fortunately, this wasn’t a factor for a team of researchers that recently combined bisulfite conversion and target capture with deep sequencing to take a snap a thorough snapshot of the methylation action in their studies and bumped into some pretty interesting data along the way.
Put Agilent SureSelect™ DNA Capture eArray to Work!
Printer acting up in the office? Why not take out your frustrations by bossing around a team of its ink-jetting relatives in the eArray production facility. That’s where SureSelect™ DNA Capture Arrays are produced. They’ll make short work of your custom array order while you work a few Sudoku puzzles. You’ll be capturing regions of interest for methylation sequencing in no time.
We know you’re not going to spend your lab bucks based on our advice alone, so get the full scoop at Agilent’s SureSelect™ DNA Capture product page and tell them we sent you!