It used to be that smaller, data-rich samples lived peacefully below the threshold of utility where they were safe from the scientific ambitions of researchers. Not anymore. Recent innovations have really come together in products like Millipore’s Magna ChIP-Seq™ Chromatin Immunoprecipitation and Next Generation Sequencing Library Preparation Kit, that have small samples scrambling for cover.
How Low Can You Go?
Nothing can inject energy into your ChIP-Seq experiments like a little sample limbo. Researchers have been pushing the limits lower for the last few years and recently the Millipore R&D crew got in on the fun. Although their protocol recommends starting with 10 ng they have pushed the Magna ChIP-Seq™ Kit down to as little 1 ng of purified ChIP DNA.
Functional Validation from ChIP to Seq
The Magna ChIP-Seq™ Kit includes a number of key features that will reduce your odds of hitting any snags in your quest for rock solid ChIP data.
- The ChIP modules are functionally tested in quantitative chromatin immunoprecipitation reactions
- Each set of library construction reagents is validated through construction and sequencing of a genomic DNA library on an Illumina Genome Analyzer II.
These validation steps are like having a miniature QC department thrown in the box without all the payroll issues.
Go Small with your ChIP-Seq
There are a lot of answers in those small samples and the Magna ChIP-Seq™ Kit has all the ingredients to help you go big with them. Check it out today.