So you’ve just wrapped up a bunch of miRNA profiling experiments and now it’s time to get functional. Like any researcher studying miRNA you probably lie awake at night asking yourself: What is it targeting? With what pathways is it involved? What happens when there is too much, or not enough of it? To help zero in on those questions and get you some Z’s, Ambion® Anti-miR™ miRNA Inhibitors and Ambion® Pre-miR™ miRNA Precursors will have you playing with miRNA levels like a yo-yo in no time. Use these slick little molecules to:
- Blitz through gain or loss-of-function studies
- Dive into dose response experiments
- Pin down miRNA target sites and validate them
Ambion® Pre-miR™ miRNA Precursors
Don’t confuse them with hairpins. These miRNA mimics are so convincing, even RISC can’t tell the difference. Ambion® Pre-miR™ miRNA Precursors are small double-stranded RNA oligos that are ready to go right from the package into your miRNA over-expression experiments. Find the Ambion® Pre-miR™ miRNA mimic you want here.
Ambion® Anti-miR™ miRNA Inhibitors
Like a cellular ShamWow® , Ambion® Anti-miR miRNA Inhibitors™ will soak up any endogenous miRNA you choose. These chemically modified, single-stranded RNA molecules allow you to see what happens when your favorite miRNA is removed from the mix. Too bad they can’t remove that annoying colleague from your workspace. Find the Ambion® Anti-miR™ miRNA Inhibitor you want here.
Go Big or Go Home: Ambion® Pre-miR™ miRNA Precursor & Ambion® Anti-miR™ miRNA Inhibitor Libraries
For those complex research questions that call for some extra muscle, you’ll want to check into Ambion® Pre-miR™ miRNA Precursor Libraries and Ambion® Anti-miR™ miRNA Inhibitor Libraries. Don’t be shy, these libraries are available off the shelf or can be made completely custom if you have some top-secret miRNAs that aren’t yet in miRBase. All precursor and inhibitor libraries are supplied.
- In 96-well plate format
- Dried down at .25 nmol
Want In On All the Function?
Sure you do. To get things started, hit up the team at Invitrogen, the homestead for all Ambion® products and they’ll get you set up with the right approach. You can reach Invitrogen’s scientists directly at:EpiScientist@invitrogen.com. How’s that for service? Please, no late night texting. That’s creepy.