CBP (catalytic domain) human recombinant expressed in E. Coli Background Information: Although originally termed histone acetyltransferases (HATs) for their lysine acetylation activity on histone N-terminal tails, p300 and its paralogue, CBP, have been shown to acetylate a variety of non-histone proteins including p53, DNA polymerase ß and nuclear import factors. p300/CBP acetylations play regulatory roles […]
- Histone Acetylation Kits and Assays
Histone Acetyltransferase
Histone acetyltransferases (HAT) are enzymes that acetylate lysine amino acids on histone proteins and play a crucial role in transcription, differentiation, and proliferation.
p300 (catalytic domain) human recombinant
Human recombinant p300 (catalytic domain) expressed in E. Coli Background Information: Although originally termed histone acetyltransferases (HATs) for their lysine acetylation activity on histone N-terminal tails, p300 and its paralogue, CBP, have been shown to acetylate a variety of non-histone proteins including p53, DNA polymerase ß and nuclear import factors. p300/CBP acetylations play regulatory roles […]
PCAF human recombinant
Human recombinant PCAF expressed in E. Coli Background Information: PCAF (p300/CBP-associated factor) is involved in acetylation of histones H3 and H4, and a number of transcription factors.
EpiSeeker Histone H4 Total Acetylation Detection Fast Kit (Colorimetric)
Product Overview: Acetylation of histones such histone H4 has been involved in the regulation of chromatin structure and the recruitment of transcription factors to gene promoters. HATs (histone acetyltransferases) and HDACs (histone deacetylases) play a critical role in controlling histone H4 actylation. Reversible acetylation of nucleosomal histone H4 is believed to correlate with potential transcriptional […]
EpiSeeker Histone H3 Total Acetylation Detection Fast Kit (Colorimetric)
Product Overview: Acetylation of histones such histone H3 has been involved in the regulation of chromatin structure and the recruitment of transcription factors to gene promoters. HATs (histone acetyltransferases) and HDACs (histone deacetylases) play a critical role in controlling histone H3 actylation. Histone acetylation is tightly involved in cell cycle regulation, cell proliferation and apoptosis. […]