Finding Epimutations in the Genome Haystack

Trying to identify DNA methylation mutations with current technologies usually requires a lot of cells, making it a lot like hunting… [ more ]

Our Favorite Findings from the Epigenomic Roadmap

For those of you with a keen eye, you’ll have already noticed the mass of Epigenomic Roadmap Studies published in… [ more ]

A cHi-C Way of Capturing Chromatin Conformation

Identifying cancer risk loci is like trying to find a key you lost somewhere in your apartment. You know that… [ more ]

Active Demethylation: TET Enzymes, 5hmC, and Buddies

5hmC was originally discovered way back in the 50’s in bacteriophages and was first observed in mammals in the 70’s,… [ more ]

Unwinding the Chromatin–Cancer Connection

There’s no denying that epigenetics and cancer are intimately intertwined, and that untangling this connection is vitally important in expanding our understanding… [ more ]