Early and less tedious cancer diagnosis can prevent future complications and improve patient outcome, however past studies have revealed that the markers of most cancers are as unique as snowflakes. An enticing solution for this heterogeneity would be to screen for any type of cancer using one detection system to ‘rule them all’. Differential DNA […]
Ever get that feeling that you forgot something? Well maybe you did, but it doesn't have to be recent epigenetics research if you scope out our Headlines each week.
Mapping the dark matter of the genome is no easy chore. Enhancers love to hide and often don’t act as expected. But thankfully, there’s a handy new CRISPR/Cas9 tool to fluoresce the genomes darkest regulatory secrets. The multiplexed editing regulatory assay (MERA) is a clever system that pushes back the limits of CRISPR/Cas9 as a […]
DNA is pretty great for a lot of reasons. There is the whole “central component of life,” of course, but DNA is also a pretty great building material. Making super-tiny, nano-scale objects seems like a really hard problem, but biology does this all the time. Life’s standard nano-brick is protein, but proteins are difficult to re-engineer, […]
Ever wanted to be able to do two things at the same time? Like work and have a social life? Eat pizza and still fit in your new purchases? Pat your head and rub your belly? While these highly important combinations remain almost impossible (at least for the EpiGenie staff), a stellar cast of scientists […]
A new paper adds another RNA modification to the list already published, but with exciting news for the epigenetics enthusiasts out there… the characterized modification is RNA 5-hydroxymethylcytosine (5hmrC), an important mark previously discovered on DNA. The laboratory of François Fuks at ULB in Brussels decided to look deeper into the presence of 5hmC on […]