Last week PLoS Genetics ran a great paper from Anders Lindroth and colleagues illustrating a mutually exclusive relationship between DNA Methylation and methylation of H3K27 in the a differentially methylation domain (DMD) of an imprinting control region (ICR). Now before we drop any more epi-breviations…. The area of focus in the study was a […]
Epigenetics and ncRNA Headlines
Get all the latest highlights from the literature and special features covering trending epigenetics, ncRNA, and gene regulation research.
With all the hype around Batman-The Dark Knight, we missed one of the most recent heroic efforts to facilitate global methylation studies. The unveiling of a Bayesian tool for methylation analysis (Batman) enables researchers to estimate absolute methylation levels across a range of CpG dense regions using methylated DNA immunoprecipitation (MeDIP) approaches combined with either […]
Last week, researchers from the Karolinska Institute and the University of London released data on an innovative approach for studying RNA-RNA interactions. Data supporting the multitude of RNA functions in our cells continues to pour in, but challenges in analyzing the effecting complexes in cellular processes persist, so we tip our hats to this team […]
miRNAs, the small but mighty inhibitors of complementary mRNA sequences, might be accused of having a Napoleon complex, but they don’t start out life itty-bitty—they are transcribed as long primary miRNAs (pri-miRNAs). Cleavage by the RNase III-like enzyme Drosha in the nucleus releases a ~70-nt stem-loop structure (pre-mRNA), which is further processed by Dicer in […]
Let the blame game begin. In addition to our lifestyle habits, our mothers could have something to do with those stubborn pounds that dont seem to shed. An interesting obesity studying involving DNA methylation has provided new evidence suggesting that obese moms give birth to kids who have a propensity to become even more obese. […]