Although it sometimes feels like there is no right way to age, intriguing insight from Down Syndrome has given insight into how disrupted nuclear architecture can push us down the wrong path. Down syndrome results from the triplication of chromosome 21 and is a leading cause of intellectual disability. However, Down syndrome is also a […]
- Bonnie Alberry
A Youthful Brain Boost via DNA Hydroxymethylation: TET1 Enters the Myelin Repair Technician’s Toolkit
Does it feel like your aging brain cells have been firing a little slower lately? Why not refresh your connection and speed up your synaptic signal transmission with a visit from your oligodendrocyte myelin repair technicians. Their youthful TET1 and DNA hydroxymethylation repair kit will bring you back to fiber-optic speeds in no time. This […]
The Intergenerational Effect of Paternal Stress: circRNAs Join the Blame Game
Although we’ve known for a while that paternal stress can lead to problems down the road for their offspring thanks to DNA methylation and histone modifications, non-coding RNAs have now come full circRNA. In their latest, a talented team from the lab of Eric Miska (University of Cambridge, UK) decided to find out which RNA […]
A Pack of Hyenas Gets the Last Laugh: Early Social Networks Change DNA Methylation and Adult Stress Indicators
Ever wonder what that pack of hyenas is laughing about? Well, it may just be your social status. But don’t stress over it too much, because they’ve given us a truly wild idea in this DNA methylation marvel: Having more friends and spending more time with them in early life makes for less stress at […]
Environmental Fountain of Youth: Enrichment Prevents Aging-Induced DNA Methylation Changes
A restricted diet, regular exercise at the gym, not drinking too much… Acts of deprivation and suffering are supposed to guide us on our quest to the foundation of youth. Thankfully, exciting new epigenetic findings show us that it’s time to learn a lesson from the hedonists by demonstrating how environmental enrichment protects us from […]