From the very beginning, EpiGenie has held a place in our hearts for non-coding RNAs. That’s why we were stoked to see that the Landes journal Epigenetics dedicated an entire issue to the enigmatic and always interesting little transcripts.
The Epigenetics: Special Focus on Non-coding RNAs in Epigenetic Regulation issue features a boatload of reviews that cover the wide range of impacts that have emerged from non-coding RNA research. Plus, several cutting-edge research papers from leaders in the field including:
- Epigenetic loss of the PIWI/piRNA machinery in human testicular tumorigenesis
Humberto J Ferreira, Holger Heyn, Xavier Garcia del Muro, August Vidal, Sara Larriba, Clara Muñoz, Alberto Villanueva and Manel Esteller - microRNA-199a-3p, DNMT3A, and aberrant DNA methylation in testicular cancer
Bi-Feng Chen, Shen Gu, Yick-Keung Suen, Lu Li and Wai-Yee Cha - Epigenetic regulation of miR-21 in colorectal cancer: ITGB4 as a novel miR-21 target and a three-gene network (miR-21-ITGΒ4-PCDC4) as predictor of metastatic tumor potential
Angelo Ferraro, Christos Kontos, Themis Boni, Ioannis Bantounas, Dimitra Siakouli, Vivian Kosmidou, Margarita Vlassi, Yannis Spyridakis, Iraklis Tsipras, George Zografos and Alexander Pintzas - miR-34a expression, epigenetic regulation, and function in human placental diseases
Ludivine Doridot, Dorothée Houry, Harald Gaillard, Sonia T Chelbi, Sandrine Barbaux and Daniel Vaiman - Prenatal stress changes the glycoprotein GPM6A gene expression and induces epigenetic changes in rat offspring brain
Melisa C Monteleone, Ezequiela Adrover, María Eugenia Pallarés, Marta C Antonelli, Alberto C Frasch and Marcela A Brocco - Massive analysis of cDNA Ends (MACE) and miRNA expression profiling identifies proatherogenic pathways in chronic kidney disease
Adam M Zawada, Kyrill S Rogacev, Sören Müller, Björn Rotter, Peter Winter, Danilo Fliser and Gunnar H Heine - A long non-coding RNA promotes full activation of adult gene expression in the chicken α-globin domain
Cristian Arriaga-Canon, Yael Fonseca-Guzmán, Christian Valdes-Quezada, Rodrigo Arzate-Mejía, Georgina Guerrero and Félix Recillas-Targa
If you love ncRNAs like we do, check out the full issue at Epigenetics, January 2014.