Based on their booming popularity lately, it seems that histone deacetylases (HDACs) and sirtuins (SIRTs) lead pretty active epigenetic lives. As the experiments continue, there are several reasons why the epigenetics research community would want to keep tabs on what HDACs and SIRTs are doing including:
- Assessing HDAC or SIRT purification
- Screening for HDAC/SIRT inhibitors or activators
- Identifying the effects of pharmacological agents on HDAC or SIRT function.
Regardless of the reason, if you need to know more about what’s happening with HDAC and/or SIRT activity, Abcam has an entire line of fluorometric HDAC and SIRT activity assays that make staying informed almost as easy as “following” a Twitter feed.
Upgrade to Abcam’s HDAC & SIRT Activity Suite
Abcam recently developed and launched a comprehensive suite of HDAC and SIRT Activity Assay Kits that allow you to quickly and sensitively monitor HDAC and SIRT levels for a variety of specific targets:
- Histone Deacetylase (HDAC) Activity Assay Kit (Covers HDAC1, 2, 3 and 8)
- SIRT1 Activity Assay Kit
- SIRT2 Activity Assay Kit
- SIRT3 Activity Assay Kit
- SIRT6 Activity Assay Kit
- HDAC8 Activity Assay Kit
HDACs can’t hide what they’ve been up to from Abcam’s activity assays.
The HDAC or SIRT Activity Assay Kits are designed for use with crude or purified samples, or when paired with the appropriate antibody or HDAC inhibitor, can even assay activity in cell lines or tissue homogenates.
Get everything you need to monitor the activity of specific HDACs and SIRTs using the links above. Or check out the Abcam website to see their complete line of epigenetic kits and assays.