FFPE samples are highly valuable for their ability to relate clinical outcomes to disease states and epigenetic profiles. Active Motif’sFFPE Bisulfite Conversion Kit is designed for DNA methylation analysis of formalin- or paraformalin-fixed, paraffin-embedded (FFPE) tissues to provide a DNA methylation profile at single-base-pair resolution. Schematic of bisulfite conversion. Since FFPE samples are […]
- DNA Methylation
Global 5-hmC Quantification Kit
Active Motif’s Global 5-hmC Quantification Kit is an ELISA-based assay designed to detect and quantify 5-hydroxymethylcytosine (5-hmC) levels in genomic DNA from different sample types (e.g. normal and diseased), treatment conditions, clinical outcomes or environmental backgrounds. The Global 5-hmC Quantification Kit enables higher throughput processing of samples, requires only nanogram amounts of genomic DNA per […]
Global DNA Methylation Assay – LINE-1
Global DNA Methylation Assay to quantify genome-wide 5-mC levels in human DNA Simple ELISA assay in a flexible strip-well microplate format Detects as low as 0.5% methylation Detects methylation from as little as 10 ng DNA/well LINE-1 probe used for DNA capture for better specificity Biologically relevant standards provided for improved quantification Active Motif’s Global […]
EpiSeeker 5-formylcytosine DNA Quantification Kit
EpiSeeker 5-formylcytosine DNA Quantification Kit (Colorimetric) is a complete set of optimized buffers and reagents to colorimetrically quantify 5-formylcytosine (5-fC) in a microplate-based format. It is suitable for use with DNA isolated from any species (mammals, plants, fungi, bacteria, viruses, etc.) in a variety of forms including, but not limited to, cultured cells, fresh and frozen […]
MethylEdge™ Bisulfite Conversion System
The MethylEdge™ Bisulfite Conversion System provides a rapid, efficient method to perform bisulfite conversion with minimal DNA fragmentation in less than two hours. The rapid protocol and complete conversion mean that you can produce completely converted DNA ready for your choice downstream assays with minimal preparation and hands-on time. Coupled with purification chemistries and flexible, robust amplification […]